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Growth Hormone & IGF Research, 2020
Melanin is what makes the skin colour, and in case of excess production or unevenness, dark spots and pigmentation would be observed
Further exploration of the mechanism of action of FTO in UM cells revealed that high expression of FTO can reduce the m 6 A level within cells, thereby affecting the expression and function of a series of downstream genes
Phosphatidylserine (PS), as a phospholipid of the renal tubular epithelial cell membrane that can adsorb crystals, flips to the cell surface, enhancing the adhesiveness of stone crystals at the flipped sites ( Joshi et al
Equally important is the hit on the selenoprotein thioredoxin reductase 1 (TXNRD1), which also was highly scored by both NetCorona and PROSPER (Figure 2E)
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